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Symbol Name ID |
Cish
cytokine inducible SH2-containing protein MGI:103159 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
increased T cell proliferation |
thymus hyperplasia |
spleen hyperplasia |
abnormal CD4-positive T cell differentiation |
abnormal T-helper 2 cell differentiation |
increased eosinophil cell number |
increased lymphocyte cell number |
abnormal immune system morphology |
lymph node hyperplasia |
abnormal immune system physiology |
increased susceptibility to type I hypersensitivity reaction |
increased interleukin-10 secretion |
increased interleukin-13 secretion |
increased interleukin-4 secretion |
increased interleukin-5 secretion |
increased interleukin-9 secretion |
lung inflammation |
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| Availability | Mouse Genotype | ||||||||||||||||||
| Cishtm1.2Cdon/Cishtm1.2Cdon | * | ||||||||||||||||||
| Cishtm1.1Cdon/Cishtm1.1Cdon Tg(Cd4-cre)1Cwi/0 (conditional) |
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| Cishtm1.1Cdon/Cishtm1.1Cdon Foxp3tm4(YFP/icre)Ayr/Foxp3+ (conditional) |
* | ||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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